Crossing - gel Analysis
- Evaluating drug toxicities using 2D DIGE (Crossing- gel Image Analysis)
Green: Control
Red: Drug 1 Green: Control
Red: Drug 2 Green: Drug 1
Red: Drug 2
Green: Control
Red: Drug 3 Green: Control
Red: Drug 4 Green: Drug 3
Red: Drug 4Clustering Analysis of Protein Toxic-marker Expression
Patterns for Toxic Compounds (1480 spots)
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Liver and kidney toxic Liver toxic Liver non-toxic
The change in expression level between control and drug treatment for 1480 protein spots is shown for each of the 18 drugs, which are grouped according to toxicity. Cluster analysis was performed with Genespring software ( Redwood City, CA).
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