Applications of 2D DIGE/Mass spectrometry

Clinical Research

1. Serum 2D DIGE (clinical trial)

2. Tumor Marker Discovery and Progress Monitoring from human biopsy

3. Biomarker Discovery from Human biopsy

4. Toxicity Evaluation and Pharmacokinetics 1

5. Toxicity Evaluation and Pharmacokinetics 2

6. Disease Model Study

7. Therapeutic Target Discovery (T-cell signaling)

8. Aminotic Fluid

Basic Research

9. Transgenic and Gene Knock-out Animal Protein Profiling and Phenotyping

10. Protein Expression Knock-down by siRNA

11. Monitoring The Gene Expression Under Different Conditions

12. Protein Phosphorylation Detection

13. Monitoring The Time-dependent Protein Expression (Stem Cell Research)

14. Immuno-precipitation: Phosphorylation-Dependent Association

15. Protein Complex Analysis

16. Kinase Target (Substrate) Identification

17. Comparing Transfected Cell Populations to Identify Gene Function

18. Sub-Cellular Protein Differential Expression (Mitochondria)

19. Gene Knock-out Protein Profiling In Bacteria

20. Protein Differential Expression in Yeast

21. Fluorescent 2-color 2-D Western blot

22. Product Quality Testing (Contamination or Lot-to-Lot Consistency)

23. 1-D DIGE Application

2D DIGE Image Library

24. 2D images (saliva sample)

25. 2D images (urine sample)

26. 2D image (E. coli)

27. 2D image (Drosophila)

28. 2D images (plant)

29. 2D Images (C. elegans)

30. 2D Images (Zebrafish)

31. 2D Images (mouse and rat brain)

32. 2D Images (Rat tears)



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