Applications of 2D DIGE/Mass spectrometry

Clinical Research

1. Serum 2D DIGE (clinical trial)

2. Tumor Marker Discovery and Progress Monitoring from human biopsy

3. Biomarker Discovery from Human biopsy

4. Toxicity Evaluation and Pharmacokinetics 1

5. Toxicity Evaluation and Pharmacokinetics 2

6. Disease Model Study

7. Therapeutic Target Discovery (T-cell signaling)

Basic Research

8. Transgenic and Gene Knock-out Animal Protein Profiling and Phenotyping

9. Protein Expression Knock-down by siRNA

10. Monitoring The Gene Expression Under Different Conditions

11. Protein Phosphorylation Detection

12. Monitoring The Time-dependent Protein Expression (Stem Cell Research)

13. Immuno-precipitation: Phosphorylation-Dependent Association

14. Protein Complex Analysis

15. Kinase Target (Substrate) Identification

16. Comparing Transfected Cell Populations to Identify Gene Function

17. Sub-Cellular Protein Differential Expression (Mitochondria)

18. Gene Knock-out Protein Profiling In Bacteria

19. Protein Differential Expression in Yeast

20. Product Quality Testing (Contamination or Lot-to-Lot Consistency)

21. 1-D DIGE Application

2D DIGE Image Library

22. 2D images (saliva sample)

23. 2D images (urine sample)

24. 2D image (E. coli)

25. 2D image (Drosophila)

26. 2D images (plant)

27. 2D Images (C. elegans)

28. 2D Images (Zebrafish)

29. 2D Images (mouse and rat brain)


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