Home > Proteomics Services >Methylation Site
This service works the best with purified proteins or IP samples with target proteins enriched. Each experiment covers the identification of ALL Mono-Methylated Lysine Sites in a single protein per sample. Customers can send samples in-gel or in-solution, and provide the amino acid sequence or accession number of the target protein.
The presence of a mono-methylated lysine residue is confirmed by the presence of an immonium ion peak at 98 m/z during MS/MS.
Gel Bands/Spots or In-Solution Samples![]() |
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Reduction/Alkylation & Trypsin Digestion![]() |
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![]() MS |
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Non-Methylated Peptide Peak![]() |
Methylated Peptide Peak![]() |
![]() MS/MS |
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Non-Methylated Peptide Peak ![]() |
Methylated Peptide Peak ![]() |
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Database Search for Mono-Methylated Lysine Sites |
If you are interested, please follow these steps to obtain more information and order this service.